Abnormal slow wave mapping (ASWAM)—A tool for the investigation of abnormal slow wave activity in the human brain

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Abnormal slow wave mapping (ASWAM)--A tool for the investigation of abnormal slow wave activity in the human brain.

Slow waves in the delta and theta frequency range, normal signs of deactivated networks in sleep stages, are considered 'abnormal' when prominent in the waking state and when generated in circumscribed brain areas. Structural cortical lesions, e.g. related to stroke, tumors, or scars, generate focal electric and magnetic slow wave activity in the penumbra. Focal concentrations of slow wave acti...

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The regulation of the timing of sleep is thought to be linked to the temporal dynamics of slow-wave activity [SWA, electroencephalogram (EEG) spectral power in the approximately 0.75-4.5 Hz range] in the cortical non-rapid eye movement (NREM) sleep EEG. In the two-process model of sleep regulation, SWA was used as a direct indication of sleep debt, or Process S. Originally, estimation of the la...

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Propagation of slow intrinsic brain activity has been widely observed in electrophysiogical studies of slow wave sleep (SWS). However, in human resting state fMRI (rs-fMRI), intrinsic activity has been understood predominantly in terms of zero-lag temporal synchrony (functional connectivity) within systems known as resting state networks (RSNs). Prior rs-fMRI studies have found that RSNs are ge...

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ژورنال

عنوان ژورنال: Journal of Neuroscience Methods

سال: 2007

ISSN: 0165-0270

DOI: 10.1016/j.jneumeth.2007.02.018